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Oral acetazolamide for Sodium valproate related weight gain in Bipolar disorder

â??Oral Acetazolamide for Sodium Valproate induced weight gain in Bipolar Affective Disorder - An open label studyâ??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/019075
Enrollment
34
Registered
2019-05-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F317- Bipolar disorder, currently in remission

Interventions

Intervention1: Oral Acetazolamide upto a maximum of 500mg per day over a period of 8 weeks on patients with Bipolar disorder who are on stable dose of Sodium Valproate.: Oral Acetazolamide upto a maxi

Sponsors

Dr Mathews Joseph Panicker
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -Out patients or in patients diagnosed as Bipolar Affective Mood Disorder using MINI PLUS and only on Sodium Valproate. -Both males and females -18 â?? 60 years of age -Without any co-morbid psychiatric illness other than nicotine use.

Exclusion criteria

Exclusion criteria: -Persons on Acetazolamide for any medical reasons. -No known medical conditions in which acetazolamide is contraindicated like hyperchloremic acidosis, hypokalemia, hyponatremia, adrenal insufficiency, impaired kidney function, hypersensitivity to acetazolamide or other sulphonamides, liver diseases. -Pregnancy, lactation -Sub normal intelligence

Design outcomes

Primary

MeasureTime frame
To assess the effect of Acetazolamide on weight when combined with Sodium Valproate in patients diagnosed with Bipolar Affective DisorderTimepoint: 8 weeks

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Mathews Joseph Panicker

Yenepoya Medical College

anilpsychiatry@yahoo.co.in9845312940

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026