FindTrial
Sign In

Role of Vitamin C and Thiamine in patients with sepsis in Indian Population: Single blind, Parallel Group, Randomized controlled trial

To study the effect of Vitamin C and Thiamine in patients with sepsis in Indian Population: Single blind, Parallel Group, Randomized controlled trial - Sepsis, Vitamin C, Thiamine

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/018992
Enrollment
250
Registered
2019-05-08
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A419- Sepsis, unspecified organism

Interventions

Intervention1: Ascorbic acid, Thiamine: Intravenous ascorbic acid (1.5g every 6 hour for 4 days until discharge but not more than 10 days will be given. Intravenous thiamine (200mg every 12 hour for

Sponsors

ICMR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients with Sepsis and/or severe sepsis

Exclusion criteria

Exclusion criteria: 1) Age: �18 years 2) Pregnant patient 3)Known autoimmune disease 4)known CKD more than 3stage, hemochromatosis, G6PD deficiency, hypersensitivity

Design outcomes

Primary

MeasureTime frame
mortality (on or before)Timepoint: 28 days—

Secondary

MeasureTime frame
length of hospital stay and change in SOFA score upto 28 daysTimepoint: 28 days (study period)—

Countries

India

Contacts

Public ContactArvind Kumar

All India Institute of Medical Sciences

linktoarvind@gmail.com8800984895

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026