Clinical study of Ayurvedic medicines namely â??Vyoshadi Gugguluâ?? and â??Shadushana Churnaâ?? in the management of subclinical hypothyroidism

A randomized comparative clinical study to evaluate the efficacy of â??Vyoshadi Gugguluâ?? and â??Shadushana Churnaâ?? in the management of Dhatvagnimandya w.s.r. to subclinical hypothyroidism

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/05/018989

Enrollment

Registered

2019-05-07

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E02- Subclinical iodine-deficiency hypothyroidism

Interventions

Intervention1: Vyoshadi Guggulu: A herbal formulation from Brihat Nighantu Ratnakar has been selected as trial drug for evaluating its probable role in the management of subclinical hypothyro

Eligibility

Inclusion criteria

Inclusion criteria: 1. Newly diagnosed patients of TSH level 5-10 mlU/l. 2. Patients having any signs and symptoms of subclinical hypothyroidism. 3. Patients willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients below 18 years and above 60 years of age. 2. TSH level more than 10 or less than 5. 3. Patients under allopathic treatment for Subclinical or clinical hypothyroidism. 4. Patients suffering from any other systemic illness viz. diabetes, HTN, liver disorders etc. 5. Pregnant and lactating patients. 6. Patients undergoing treatment for any other systemic illness. 7. Patient participated in any clinical trial within last six months.

Design outcomes

Primary

Measure	Time frame
Any changes in the values of Serum TSH.Timepoint: 60 days	—

Secondary

Measure	Time frame
Changes in specific symptoms of subclinical hypothyroidism.Timepoint: 60 days	—

Countries

India

Contacts

Public ContactDr Vidhya Bharti Sharma

National Institute of Ayurveda

hari_mohan68@yahoo.co.in9461297017

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026