Health Condition 1: L700- Acne vulgaris
Conditions
Interventions
Intervention1: Isotretinoin: Isotretinoin 20mg once daily for 3 months
Control Intervention1: Isotretinoin compared with isotretinoin with desloratidine: Isotretinoin 20 mg once daily will be given to
Sponsors
Dr Neirita Hazarika
Eligibility
Inclusion criteria
Inclusion criteria: 1. Consenting patients 2. Moderate acne and severe acne 3. Patients presenting to us for the first time (new cases), who have not received retinoids in last 6 months
Exclusion criteria
Exclusion criteria: • Pregnant and lactating women • Women planning pregnancy • Patients receiving antihistamines for other disorders • Patient on acne treatment in tha last 4 weeks and on topical treatment in last 2 weeks • Patients receiving any treatment likely to worsen the acne treatment, like steroids in alst 4 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in acne severity assessed by : decrease in total inflammatory lesion count measured during each visit until 12 weeks Improvement in global acne grading score at the end of 3months Improvemnet in acne severity assessed by participants self assessment sTimepoint: 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Improvement in acne severity assessed by the patient using participants selfâ??assessment of acne severity (very satisfied to unsatisfied) 2. Changes in quality of life (QoL) assessed using a validated instrument. 3. Frequency of less serious adverse effects. 4. Dropout rates. Timepoint: 12 months | — |
Countries
India
Contacts
Public ContactDr Neirita Hazarika
AIIMS Rishikesh
Outcome results
None listed