Health Condition 1: F31- Bipolar disorder Health Condition 2: F313- Bipolar disorder, current episodedepressed, mild or moderate severity
Conditions
Interventions
Intervention1: HD tdcs: The Starstim 32 is a wearable device that wirelessly transmits the 32-channel data via wifi. Its hybrid electrodes can be used for electrical stimulation (tDCS). It Synchronize
0-500 Hz (tRNS) where Data transmission will be wireless (wi-fi network) or wired (USB cable).
Control Intervention1: not applicable: not applicable
Sponsors
CENTRAL INSTITUTE OF PSYCHIATRY
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of bipolar affective disorder according to diagnostic criteria of research of ICD 10 Bipolar affective disorder current episode manic with or without psychotic symptoms Age group between 18 to 45 yrs of age of either sex Patients who is drug free or drug naive for a minimum of 8 weeks Patients giving written informed consent YMRS score of more than greatyer and equal to 10
Exclusion criteria
Exclusion criteria: Presence of comorbid neurological or other psychiatric disorder History of epilepsy sustained brain damage or any neurological procedures Subjects who have received ECT or rTMS in past 2 months Developmental delay or mental retardation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome of the study is change in GDNF levels in patients with Bipolar Affective Disorder with improvement in mood states.Timepoint: At baseline ,before application of HDtdcs and after application of HDtdcs | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are changes in Psychopathology scores as measured by YMRS after application of HD-tDCS.Timepoint: At baseline, before application of HDtdcs and after application of HDtdcs | — |
Countries
India
Contacts
Public ContactDr Nishant Goyal
Central Institute of psychiatry
Outcome results
None listed