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To compare lignocaine alone and in combination with dexmedetomidine for intravenous regional anaesthesia for upper limb surgery.

A study to compare the anaesthetic properties of 0.5% alone and in combination with dexmedetomidine for intravenous regional anaesthesiain patients undergoing upper limb orthopaedicsurgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/018918
Enrollment
60
Registered
2019-05-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous regional anaesthesia: Onset of motor and sensory block Control Intervention1: 0.5 % lignocaine alone and in combination with Dexmedetomidine: To reduce the dose of lignocain

Sponsors

Jln Medical College ajmer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age between 20 to 55 years, of either sex. 2.Body weight 35 to 80 kg. 3.Patients belonging to ASA Class I and II. 4. Patients undergoing upper limb surgeries of duration less than 45 minutes. 5.Patient free from any associated acute or chronic systemic illness.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications to tourniquet application like sickle cell anemia, cellulitis, sepsis, open wound in that extremity, etc. 2. Patients hypersensitive to lignocaine 3. Patient not willing for IVRA 4. Patient already on analgesics (opioids, NSAIDS) 5. Patients receiving beta blockers or cardiac drugs. 6. History of convulsion, allergy to the drug used, bleeding disorder, severe neurological deficit, thyroid disorder. 7. Patient with history of respiratory, cardiac, hepatic or renal disease (necessitating classification in ASA Class III or above). 8. Inadequate block necessitating institution of general anaesthesia for continuation of surgical procedure.

Design outcomes

Primary

MeasureTime frame
Quality and duration of post-operative analgesiaTimepoint: duration of study is around 1 year

Secondary

MeasureTime frame
1.Torniquet pain. 2. Need for analgesic supplements 3. Post operative sedation 4. Adverse effects including nausea, vomiting, bradycardia, hypotension, desaturation and others, if anyTimepoint: Duration of study is around 1 year

Countries

India

Contacts

Public ContactDr Neena jain

Jln Medical College ajmer

drneenaj@gmail.com9414008666

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026