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Comparison between two anaesthetic drugs Propofol and Ketamine during anaesthesia in Electro Convulsive Therapy in treatment of depressive disorders.

Comparative Effects of Propofol and Ketamine For modified ECT; a prospective randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/018890
Enrollment
44
Registered
2019-05-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F333- Major depressive disorder, recurrent, severe with psychotic symptoms

Interventions

Intervention1: Inj Propofol and Inj Ketamine: induction of modified ECT by inducing agents INJ Propofol 1.5 mg / Kg IV or Inj Ketamine 0.8-1.2 mg/ Kg IV Intervention2: Inj Propofol: induction by Inj

Sponsors

Armed Forces Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients of age more than 18 yrs scheduled for ECT

Exclusion criteria

Exclusion criteria: 1. Patients not giving consent 2. Raised intracranial pressure 3. Pregnancy

Design outcomes

Primary

MeasureTime frame
comparison of Duration of seizure (both motor and EEG) between Propofol and Ketamine when used in modified ECTTimepoint: outcome will be assessed immediately after administering the drug till the time the seizure will last.

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDebarshi Guha

Armed Forces Medical College

drnsethi@yahoo.co.in8879526556

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026