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Oral Acetazolamide for drug related weight gain

Oral Acetazolamide for Antipsychotic induced weight gain â?? An open label study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/05/018884
Enrollment
34
Registered
2019-05-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F209- Schizophrenia, unspecified

Interventions

Intervention1: Oral Acetazolamide upto a maximum of 500 mg per day over a period of 8 weeks on patients who are on antipsychotics-- Risperidone/Olanzapine (Which is Treatment As Usual): Oral Acetazola

Sponsors

Anupama Priyamkari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Out patients or in patients diagnosed as schizophrenia, schizoaffective disorder, delusional disorder, psychosis NOS, Non organic psychosis diagnosed using MINI PLUS Both males and females 18 â?? 60 years of age Patients who are treated with Risperidone or Olanzepine Patients who are drug naïve, off medication for atleast 6 months or have been on psychotropic medications for less than 1 month. Without any co-morbid psychiatric illness other than nicotine use

Exclusion criteria

Exclusion criteria: Persons on Acetazolamide for any medical reasons. No known medical conditions in which acetazolamide is contraindicated like hyperchloremic acidosis, hypokalaemia, hyponatremia, adrenal insufficiency, impaired kidney function, hypersensitivity to acetazolamide or other sulphonamides, liver diseases. Pregnancy, lactation Sub normal intelligence

Design outcomes

Primary

MeasureTime frame
To test the effect of Acetazolamide on weight induced by AntipsychoticsTimepoint: 8 weeks

Secondary

MeasureTime frame
To assess in Brief Psychiatric Rating Scale score on patients receiving acetazolamideTimepoint: 8 weeks

Countries

India

Contacts

Public ContactDr Anupama Priyamkari

Yenepoya Medical College

anilpsychiatry@yahoo.co.in9845312940

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 11, 2026