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Correlation of anti-acetylcholine antibodies with progression of blistering disease - pemphigus

A prospective study of correlation of acetylcholine receptor antibody titres with clinical activity in pemphigus disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/05/018881
Enrollment
20
Registered
2019-05-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L100- Pemphigus vulgaris

Interventions

None listed

Sponsors

Indian Association of Dermatology venereology and leprosy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: confirmed cases of pemphigus disease after taking informed consent.

Exclusion criteria

Exclusion criteria: Patients not willing to participate in the study Myasthenia Gravis Lambert-EAton syndrome Small cell carcinoma of lung Systemic lupus erythematosus

Design outcomes

Primary

MeasureTime frame
Autoimmune Bullous skin disorder intensity score (ABSIS) and Pemphigus disease activity index (PDAI) will be calculated at 0, 1 and 6 months Acetylcholine antibodies will be estimated at 0, 1 and 6 months desmoglein antibodies will be estimated at 0,1 and 6 monthsTimepoint: Autoimmune Bullous skin disorder intensity score (ABSIS) and Pemphigus disease activity index (PDAI) will be calculated at 0, 1 and 6 months Acetylcholine antibodies will be estimated at 0, 1 and 6 months desmoglein antibodies will be estimated at 0,1 and 6 months—

Secondary

MeasureTime frame
tires of acetylcholine and desmoglein ELISATimepoint: baseline, 1 month and 6 months—

Countries

India

Contacts

Public ContactAnuradha Jindal

Kasturba Medical college, Manipal Academy of higher education

raghavrao1@gmail.com8296628665

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026