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A clinical trial to study the role of increased serum total bilirubin level as a new tool to detect complicated appendicitis.

Evaluation of role of hyperbilirubinaemia as a new diagnostic marker of complicated appendicitis.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/05/018879
Enrollment
110
Registered
2019-05-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K353- Acute appendicitis with localizedperitonitis

Interventions

None listed

Sponsors

Bankura Sammilani Medical College and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All the cases of clinically diagnosed acute appendicitis of age 5 years and above scheduled for appendectomy at emergency surgical unit of this hospital, will be taken for study.Diagnosis will be confirmed by histopathological examination.

Exclusion criteria

Exclusion criteria: a. Patients of age below 5 years b. Patients with appendicular lump fromation c. All patients documented to have a past history of i. Jaundice or Liver disease with hyperbilirubinaemia ii. Chronic alcoholism (i.e. intake of alcohol of >40g/day for Men and >20g/day in Women for 10 years24) iii. Hemolytic disease iv. Acquired or Congenital biliary disease. d. Patients with positive HbsAg and/or with recent history of jaundice. e. Patients with history of gastro intestinal malignancy. f. History of hepatotoxic drug use â?? past/recent. g. All patients with cholelithiasis

Design outcomes

Primary

MeasureTime frame
In this study, significantly elevated serum total bilirubin level(1.0 mg/dl) may be observed in majority of cases with complicated(i.e gangrenous/perforative) appendicitis than those with simple appendicitis and the bilirubinaemia will be mixed type (both direct and indirect bilirubin will be elevated).Timepoint: 12 Months

Secondary

MeasureTime frame
new data regarding serum hyperbilirubinaemia in pregnant acute appendicitis patients may come up.Timepoint: 12 Months

Countries

India

Contacts

Public ContactDrSabyasachi Bakshi

Bankura Sammilani Medical College and hospital

dr.bakshi.s@gmail.com9051215779

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 16, 2026