â?? Role of Punarnava Mandura and Kanchanara-Shunthi Kwatha in the Dhatwagnimandya ((Hypothyroidism)

Comparative Evaluation of Punarnava Mandura and Kanchanara-Shunthi Kwatha in the management of Dhatwagnimandya W.S.R. to Hypothyroidism

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/04/018867

Enrollment

Registered

2019-04-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E039- Hypothyroidism, unspecified Health Condition 2: null- Patients having symptoms of Dhatwagnimandya (Hypothyroidism)

Interventions

Intervention1: 1. Punarnava Mandura 2. Kanchanara-Shunthi Kwatha: 1. Punarnava Mandura â?? 500mg, twice in a day with honey before meal for 45 days. 2. Kanchanar Shunthi Kwatha â?? 40ml, twice in a

Eligibility

Inclusion criteria

Inclusion criteria: A subject will be eligible for inclusion in this study only if all of the following criteria applied: 1 Patients between the age of 18-60 years of either sex. 2 Patients having sign and symptoms of Primary Hypothyroidism. 3 Patients who are already diagnosed as hypothyroidism and under Levo-thyroxine medication but still presenting with the increased TSH level

Exclusion criteria

Exclusion criteria: A subject will not be eligible for inclusion in this study if any of the following criteria applied: 1 Patients below 18 yrs and above 60 yrs of age. 2 TSH level above 30ÂµIU/ml. 3 Patients suffering from congenital hypothyroidism and secondary hypothyroidism. 4 Pregnant women, hyperthyroidism, neoplasia, toxic goitre are excluded. 5 Patients who have under gone any type of thyroid surgery. 6 Patients whose symptoms are worsely aggravated after leaving the modern drug Levo-thyroxine (for washout period). 7 Mentally ill/ Retarded patients. 8 Drug induced hypothyroidism.

Design outcomes

Primary

Measure	Time frame
Improvement in sign and symptom of Dhatwagnimandya (Hypothyroidism)Timepoint: Assessment of 15th,30th and on completion of trial i.e. on 45th day	—

Secondary

Measure	Time frame
1 Improvement in thyroid profile 2 Comparison of effect of Punarnava Mandura , Kanchanara-Shunthi Kwatha and Tab Thyrin in Dhatwagnimandya (Hypothyroidism)Timepoint: Assessment of 15th,30th and on completion of trial i.e. on 45th day	—

Countries

India

Contacts

Public ContactDr Meenakshi Gautam

National Institute of Ayurveda

gautamdrmeenakshi@gmail.com9680556545

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026