Health Condition 1: J159- Unspecified bacterial pneumonia
Conditions
Interventions
Intervention1: Use of 2 different modes of administration of an antibiotic and compare the efficacy.: Use of Colistin in gram negative Ventilator Associated Pneumonia as Intermittent dosing regime.
Co
Sponsors
dr simranpreet singh
Eligibility
Inclusion criteria
Inclusion criteria: Children of age 1 month to 18yrs suffering from VAP as per CPIS score and microbiological evidence of gram negative organism in culture specimen
Exclusion criteria
Exclusion criteria: any patient with gram positive organism growth or sensitivity to a lower class of antibiotic. Also patients who leave against medical advice or those with untimely mortality during study duration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of intermittent dose regime and continuous infusion of intravenous colistin in terms of clinical and microbiological outcome in the treatment of children with ventilator associated pneumonia.Timepoint: Negative CPIS scores and microbiological clearance documentation in the diagnostic specimen at day 4 or day 7 of treatment whichever applicable | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To study any difference in incidence of adverse effects of colistin when given by either of these methodsTimepoint: Negative CPIS scores and microbiological clearance documentation in the diagnostic specimen on day 4 or day 7 of treatment whichever applicable | — |
Countries
India
Contacts
Public ContactDR SIMRANPREET SINGH
PICU incharge. Sir gangaram hospital
Outcome results
None listed