A Clinical trial to study the effect of Probiotics on Parkinsons Disease at 12 weeks

Effect of Probiotics on Movement Disorder Society -Unified Parkinsons Disease Rating Scale in Parkinsons Disease at 12 weeks-A Randomised Controlled Trial - PIPD

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/04/018846

Enrollment

Registered

2019-04-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G20- Parkinsons disease

Interventions

Intervention1: Probiotics: probiotic sachet containg Streptococcus faecalis 30 million, Clostridium butyricum 2 million, Bacillus mesentericus 1 million, Lactobacillus sporogenes Control Intervention1

Eligibility

Inclusion criteria

Inclusion criteria: 1.Signed informed consent. 2.Hoehn & Yahr score of 2-3 in OFF state 3.Age of motor symptoms onset > 50 years

Exclusion criteria

Exclusion criteria: 1.Those taking anti oxidant supplements 2.Those taking anti inflammatory medications 3.Thoase taking pre and probiotics as medications 4.Those who has taken antibiotics in the last 1 month 5.First degree relative or more than one relative with Parkinsons Disease 6.Diagnosis of dementia (DSM-V criteria) 7.Diagnosis of major depression or psychosis (DSM-V criteria) 8.Smokers

Design outcomes

Primary

Measure	Time frame
Primary outcome is assessed by the Movement Disorder Society-Unified Parkinsons Disease Rating Scale, which has four parts. Part I non-motor experiences of daily living-13 items. Part II motor experiences of daily living-13 items. Part III motor examination 33 scores based on 18 items several with right left or other body distribution scores and Part IV motor complications 6 itemsTimepoint: 12 weeks	—

Measure

Time frame

Primary outcome is assessed by the Movement Disorder Society-Unified Parkinsons Disease Rating Scale, which has four parts. Part I non-motor experiences of daily living-13 items. Part II motor experiences of daily living-13 items. Part III motor examination 33 scores based on 18 items several with right left or other body distribution scores and Part IV motor complications 6 itemsTimepoint: 12 weeks

—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr GITHIN BENOY GEORGE

GOVERNMENT MEDICAL COLLEGE, THIRUVANANTHAPURAM

drthomasiypeneuro@gmail.com9446230317

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026