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Study to reduce infection of wound in emergency abdominal operations

Comparison of bundle approach with conventional approach for surgical site infection prevention in cases of exploratory laparotomy for peritonitis: a double blinded randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018840
Enrollment
68
Registered
2019-04-30
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K650- Generalized (acute) peritonitis

Interventions

Intervention1: Bundle approach: 1.Abdominal wall Skin painting with Chlorhexidine solution 2.Normal saline irrigation of the mid-line laparotomy wound then 10% aqueous povidone iodine dabbing before

Sponsors

All India Institute of Medical Sciences Bhubaneshwar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients presenting to emergency with features of peritonitis who are planned for emergency mid-line laparotomy.

Exclusion criteria

Exclusion criteria: a) Patients with peritonitis undergoing re-exploration for complications of previous surgery. b) Patients who did not give consent to participate in study c) Previous mid-line laparotomy scar. d) Known case of allergy to povidone iodine or chlorhexidine. e) Pregnancy

Design outcomes

Primary

MeasureTime frame
To compare the rate of surgical site infections in patients with peritonitis undergoing emergency mid-line laparotomy by bundle approach with conventional approachTimepoint: 30 days (Daily after 48 hours of the surgery till the patient is discharged as per discharge criteria, then follow up in general surgery OPD with minimum two visits on post-operative day 15 and day 30.

Secondary

MeasureTime frame
To isolate the commonly implicated micro-organisms in surgical site infectionTimepoint: 30 days;To measure post operative stay in hospital (In cases of surgical site infections v/s no surgical site infections)Timepoint: 30 days;To see for the rate of wound dehiscenceTimepoint: 30 days

Countries

India

Contacts

Public ContactVikram V S

All India institute of medical sciences, Bhubaneshwar

manash67@gmail.com9937025779

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 27, 2026