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Change of drug treatment for lung infection in children.

Effectiveness of early streamlining of antibiotics vs. conventional therapy In pediatric severe pneumonia : An open label Randomized Trial - ABx LRI

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018836
Enrollment
60
Registered
2019-04-30
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J159- Unspecified bacterial pneumonia

Interventions

Intervention1: Antibiotics: Early change of intravenous to oral antibiotics in severe pediatric pneumonia Amoxyclav - 80mg/kg/day Q12H Ceftriaxone-100mg/kg/day Q12H for a duration of 2 days follow

Sponsors

Jawaharlal Institute of Post graduate Medical Education Research Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children of age 6 months to 5 years admitted as a case of severe pneumonia in JIPMER with having clinical improvements ( afebrile > 24 hours, hemodynamic stability, progressively reducing WBC count, ESR) after therapy for 2 days.

Exclusion criteria

Exclusion criteria: 1) Children with complications of pneumonia like empyema, necrotizing pneumonia, extrapulmonary infection such as meningitis, arthritis, pericarditis. 2) Immunocompromised children 3) Intensive care unit admission at the time of first evaluation

Design outcomes

Primary

MeasureTime frame
To study the duration of hospital stay between the conventional therapy and early streamlined groupTimepoint: At discharge.

Secondary

MeasureTime frame
Readmissions Cost of treatment between the 2 groups Timepoint: Follow up visit at 1 week and 1 month

Countries

India

Contacts

Public ContactShapna Lakshmi T

Jawaharlal Institute Of Postgraduate Medical Education and Research

drnbiswal@yahoo.com9442528402

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026