Health Condition 1: E785- Hyperlipidemia, unspecified
Conditions
Interventions
Intervention1: Gomutradi Kshara: Gomutradi Kshara in dose of 1 capsule (500 mg) thrice in a day with lukewarm water for 30 days.
Control Intervention1: Tablet Shuddha Guggulu (Commiphora Mukul) (Ext
Sponsors
National Institute of Ayurveda
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients between the age group of 18-60 years of either sex. 2. Diagnosed & confirmed cases of Dyslipidaemia ( Medoroga) on the basis of criteria given by NCEP-ATPIII. (If any one of the following) a) Serum Cholesterol >= 200 mg/dl b) Serum Triglycerides >= 150 mg/dl c) LDL Cholesterol >= 130 mg/dl d) HDL Cholesterol 3. Willing and able to participate in the study for 1 months.
Exclusion criteria
Exclusion criteria: 1. Patients having medical history of- a) Unstable angina b) Patients who have a past history of Atrial Fibrillation, Acute Coronary Syndrome, Myocardial Infarction, Stroke or severe Arrhythmia in the last six months. c) Patients on prolonged ( > 6 weeks) medication with corticosteroids, antidepressants, anticholinergics, immunosuppressants, oestrogen replacement therapy etc. or any other drugs that may have an influence on the outcome of the study. d) Symptomatic patient with clinical evidence of Heart failure. e) Patients with poorly controlled hypertension (systolic >160 and diastolic >100 mm of Hg) f) Uncontrolled Diabetes Mellitus. g) Impaired Renal function (Creatinine >2mg/dl). h) ALT and AST > 2 times of upper limit of normal (40 mg/dl). i) Hypothyroidism. j) Patients with evidence of malignancy. k) Patients on oral contraceptives. l) Alcoholics and /or drug abusers. m) Hypersensitivity to any of the trial drugs or their ingredients. n) Patients who have completed participation in any other clinical trial drugs or their ingredients. o) Patients who have received any cholesterol lowering medication (Modern Drug within last two weeks. 2. Pregnancy, Lactation and patients having Dyslipidaemia due to drugs e.g. Glucocorticoids ,Diuretics etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in signs and symptoms of Medoroga (Dyslipidaemia)Timepoint: Assessment on 15th and on completion of trial i.e. on 31st day | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Improvement in lipid profile 2 comparison of effect of Gomutradi Kshara and Suddha Guggulu (extract) in Medoroga (Dyslipidaemia).Timepoint: Assessment on baseline and after completion of trial i.e. on 31st day. | — |
Countries
India
Contacts
Public ContactDr Rama Kaswan
National Institute of Ayurveda
Outcome results
None listed