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use of bone grafts for bone defects

EFFECT OF PLATELET RICH FIBRIN AND DEMINERALIZED FREEZE DRIED BONE ALLOGRAFT IN COMBINATION WITH SINGLE FLAP APPROACH IN THE REGENERATIVE TREATMENT OF INTRAOSSEOUS DEFECTS - A RANDOMIZED CONTROLLED CLINICAL TRIAL. - SFA

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018785
Enrollment
10
Registered
2019-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: single flap approach WITH PRF and BONE GRAFT: patients will be followed up at 1 and 6 months Control Intervention1: Single Flap Approach with bone graft: patients will be followed up at

Sponsors

Manipal College Of Dental SciencesMangalore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients who agree to participate in the study by signing the informed consent. 2.Age >=18 years 3.Full mouth plaque index score 4.Patients diagnosed with chronic periodontitis. 5. Presence of at least one intra-osseous defect with presurgical PD >= 5 mm and radiographic depth (as assessed on periapical radiograph) >= 3 mm; limited to no extension of the periodontal intraosseous defect on the lingual/palatal side as assessed by pre-operative bone sounding.

Exclusion criteria

Exclusion criteria: 1. Patients with systemically compromised health. 2. Periodontal surgical treatment during the previous 24 months in the involved site. 3. Pregnant or lactating women. 4. Non-compliant patients. 5. Restorations and superficial caries in the area to be treated. 6. Fully restored teeth. 7. Third molars and teeth with grade III mobility 8. furcation involvement 9. inadequate endodontic treatment and/or restoration

Design outcomes

Primary

MeasureTime frame
Probing pocket depth reduction clinical attachment level gain change in gingival recession defect fill defect resolution Timepoint: baseline(0 days) and 6 months.

Secondary

MeasureTime frame
change in buccal recessionTimepoint: baseline, 3 months and 6 months

Countries

India

Contacts

Public ContactRAZIA HAIDRUS

MANIPAL COLLEGE OF DENTAL SCIENCES,MANIPAL ACADEMY OF HIGHER EDUCATION,MANGALORE

deepa.gkamath@manipal.edu9448454788

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026