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comparing effects of two drugs in supraclavicular block for upper limb surgeries

A Comparative evaluation of magnesium sulphate versus clonidine with levobupivacaine for ultrasound guided supraclavicular brachial plexuses block for upper limb surgeries: A Double blind comparative study

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018780
Enrollment
60
Registered
2019-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: GROUP A: 18 ml of 0.5 % Bupivacaine + 7 ml of 2 % xylocaine with adrenaline + 30 mcg of clonidine in 2 ml of normal saline Control Intervention1: GROUP B: 18 ml of 0.5 % levobupivacaine

Sponsors

Dr Archana
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • ADULTS belonging to American Society of Anaesthesiologists grade 1 or 2 ASA 1- Normal healthy individuals ASA II-Patient with mild systemic disease which include current smoker, social drinker,BMI-30 to40,well controlled Diabetes mellitus and hypertension , mild lung disease • Age : above 18 yrs • Surgeries involving the upper limb (forearm and hand) lasting for 1 ½ to 2 hours

Exclusion criteria

Exclusion criteria: 1 Hypersensitivity to local anaesthetic agents 2 Pregnant women 3 Pre-existing peripheral neuropathy 4 Neuro- psychiatry disorder, patients on psychotropic drugs for a prolonged period 5 Bleeding disorders, anti coagulant therapy or deranged coagulation profile

Design outcomes

Primary

MeasureTime frame
1. To compare the onset of sensory and motor block between two groups: group A Clonidine and group B magnesium sulphateTimepoint: immediately after block-in first minute after giving block

Secondary

MeasureTime frame
To compare duration of sensory and motor block between two drugsTimepoint: In postoperative period till patient feels pain- hours

Countries

India

Contacts

Public ContactARCHANA

PONDICHERYY INSTITUTE OF MEDICAL SCIENCES

ranjanrv2005@gmail.com9600823772

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026