“A Clinical Study to see the effectiveness of Guda-Haritaki (Jaggery with Terminalia Chebula fruit) in Kaphaja Pratishaya (Allergic Rhinitis) in children ?

A Randomized Controlled Clinical Study on the efficacy of Guda-Haritaki in Kaphaja Pratishaya with special reference to Allergic Rhinitis in children

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/04/018778

Enrollment

156

Registered

2019-04-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J310- Chronic rhinitis

Interventions

Intervention1: Oral administration of Study drug (Guda-Haritaki) and control drug (Guda-Shunthi).: Study drug (Haritaki) and control drug (Shunthi) will be administered with equal quantity of Guda. Th

Eligibility

Inclusion criteria

Inclusion criteria: Children are with symptoms of Kaphaja Pratishaya (Allergic Rhinitis) of age 6 to 12 years1. Patients will be selected irrespective of sex and religion. Patients, whose parents are willing to participate their child in the study and are ready to sign informed consent form will be selected for the study. Children with symptoms of Allergic Rhinitis occur for > 4 days per week and / or for > 4 consecutive weeks at a time. The laboratory finding of increased numbers of eosinophils in the nasal mucosal smear (presence of > 4 % eosinophils for 6 to 10 years of age and >10 % eosinophils for 11 to 12 years of age) and elevated Total Serum IgE concentration ( > 20 IU/ml)that patients will be selected.

Exclusion criteria

Exclusion criteria: Patients with nasal abnormalities like D.N.S., Nasal polyps, adenoid and tonsilar hypertrophy. Patients with acute respiratory infection or severe concomitant disease (Tuberculosis, Pneumonia). Malnourished child.

Design outcomes

Primary

Measure	Time frame
To evaluate the effect on change in symptoms (Nasal congestion, Nasal obstruction, Nasal itching, Clear Rhinorrhea, Sneezing and conjuntival irritation) of Allergic Rhinitis at 28th day. To evaluate the effect on change in eosinophils in nasal smear, serum IgE concentration and Absolute eosinophil count (AEC) at 28th day.Timepoint: 28th day.	—

Secondary

Measure	Time frame
To evaluate the effect on change in symptoms (Nasal congestion, Nasal obstruction, Nasal itching, Clear Rhinorrhea, Sneezing and conjuntival irritation) of Allergic Rhinitis at 14th day. Quality of life in children with Allergic Rhinitis at the first follows up visit i.e. at 14th day, 28th day and on 45th day.Timepoint: 14th day, 28th day and on 45th day.	—

Countries

India

Contacts

Public ContactAmol Sheshrao Patil

Government Ayurved College nanded

drdbchavan@gmail.com9422174644

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026