Comparison of two drugs ,intravenous lidocaine and ketamine infusion for analgesic efficacy in patients of modified radical mastectomy

Comparative evaluation of intravenous lidocaine and ketamine infusion for analgesic efficacy in modified radical mastectomy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/04/018745

Enrollment

Registered

2019-04-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Lidocaine: Intravenous Bolus 1.5mg/kg of lidocaine after induction of anesthesia followed by Infusion 1mg/kg/hour till the end of surgery in MRM for analgesic efficacy Control Intervent

Eligibility

Inclusion criteria

Inclusion criteria: Female patients of age between 18 to 65 years, undergoing Modified Radical Mastectomy (MRM) surgery under General Anaesthesia (GA). Patients willing to give informed written consent

Exclusion criteria

Exclusion criteria: History of anaphylaxis or allergy to the study drugs ASA 3 and ASA 4 patients Patient having renal,hepatic dysfunction or cardiovascular dusfunction (ejection fraction History of chronic pain BMI more than and equal to 30kg/m square Psychaitric disorders or drug abuse Chronic use of opioids or alcohol

Design outcomes

Primary

Measure	Time frame
To compare the effects of intravenous lidocaine and intravenous ketamine infusion on intra operative analgesic consumptionTimepoint: Baseline 5mins 10mins 15mins 20 mins 25mins 30mins Every 10 mins thereafter till end of surgery	—

Secondary

Measure	Time frame
To compare the effects of intravenous lidocaine and intravenous ketamine infusion on 24 hours post operative analgesic consumptionTimepoint: 24 hours	—

Countries

India

Contacts

Public ContactRajvir Kaur

Guru Gobind Singh Medical College and Hospital

drsarvjeetk@gmail.com9915680508

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026