Health Condition 1: S324- Fracture of acetabulum
Conditions
Interventions
Intervention1: Group B: Patients receive a bolus of Tranexamic Acid 10mg/kg bolus, over 10 min followed by continuous infusion of 1 mg/kg/h for 4hours.: Patients receive a bolus of Tranexamic Acid 10m
Sponsors
All India Institute of Medical Sciences
Department of Anesthesiology Pain Medicine and Critical Care AIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA physical status 1 and 2 2.Patients undergoing surgery for pelviacetabular fracture under regional anaesthesia.
Exclusion criteria
Exclusion criteria: 1.Patients with a history of severe ischaemic heart disease, 2.Patients with pulmonary embolism, deep vein thrombosis (DVT), hepatic or renal failure. 3.Patients allergic to tranexamic acid, and 4.Patients on long term anticoagulant therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measure: Total blood loss during intra and post operatively up to 24 hrs.Timepoint: Primary outcome measure: Total blood loss during intra and post operatively up to 24 hrs. | — |
Secondary
| Measure | Time frame |
|---|---|
| (1)Total blood transfusion during intra and post operatively up to 24hrs. (2) Adverse effects due to tranexamic acid, Deep vein thrombosis up to 24 hrs.Timepoint: up to 24hr after surgery | — |
Countries
India
Contacts
Public ContactMUKKELLI VINAY GANDHI
Professor, JPNATC Department of Anaesthesiology, Pain Medicine and Critical Care
Outcome results
None listed