Effects of oral melatonin and gabapentin on tube placement in trachea for anaesthesia in patient posted for surgery

Effects of oral Melatonin and Gabapentin on Attenuation of Haemodynamic response to Tracheal intubation - A Prospective Randomized Double Blind Comparative Study.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/04/018717

Enrollment

Registered

2019-04-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA Grade I and II, Normal Healthy Patient Posted for Elective Surgery Health Condition 2: K801- Calculus of gallbladder with othercholecystitis Health Condition 3: N200- Calculus of kidney Health Condition 4: K77- Liver disorders in diseases classified elsewhere Health Condition 5: C50- Malignant neoplasm of breast Health Condition 6: C260- Malignant neoplasm of intestinal tract, part unspecified Health Condition 7: K45- Other abdominal hernia Health Condition 8: K631-

Interventions

Intervention1: Oral study drugs 120 min before induction of anaesthesia: To study Haemodynamic responses to both drugs Control Intervention1: Tablet Gabapentin: Oral Gabapentin 800 mg in study group w

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I and II Posted for elective Surgery

Exclusion criteria

Exclusion criteria: Patients having history of treatment with study drug Difficult Intubation (Mallampati grade 3 and 4) Mentally ill Patient History of Drug allergy Cardiac Disease Pregnant Patients

Design outcomes

Primary

Measure	Time frame
SBP,DBP,MAP,HRTimepoint: Just after intubation,1min,3min,5min,10min	—

Secondary

Measure	Time frame
Any drug related side effectsTimepoint: till 24 hours after surgery	—

Countries

India

Contacts

Public ContactAnita Birda

Maharana Bhupal Government Hospital

anitabirda05@gmail.com9460865914

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026