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Use of carotid ultrasound to predict response to volume infusion in patients undergoing coronary artery bypass surgery.

Comparison of carotid blood flow, corrected carotid flow time and respiratory variation in carotid peak systolic velocity in predicting fluid responsiveness during Coronary Artery Bypass Grafting.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018707
Enrollment
45
Registered
2019-04-24
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I20-I25- Ischemic heart diseases

Interventions

Intervention1: Bolus of intravenous fluid: In each subject, 15 minutes after anaesthetic induction, carotid doppler will be used to assess carotid artery blood flow, corrected carotid flow time and re

Sponsors

Jawaharlal Institute of Postgraduate Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 40-65 years, ASA II-III undergoing elective isolated Coronary Artery Bypass Graft (CABG) procedure in JIPMER will be included in the study

Exclusion criteria

Exclusion criteria: 1. Significant valvular pathology 2. Hemodynamically significant arrhythmias 3. Preexisting history of cerebrovascular disease 4. LVEF less than 45% 5. Any significant peripheral vascular disease 6. Carotid artery stenosis more than 50 % by pre-operative carotid Doppler

Design outcomes

Primary

MeasureTime frame
To determine the correlation of carotid Doppler derived indices like carotid blood flow, corrected carotid flow time and respiratory variations in carotid peak systolic velocity for fluid responsiveness in mechanically ventilated patients undergoing Coronary Artery Bypass Grafting surgery and compare the predictive values of the three parameters to find out which of these parameters best predicts response to a fluid bolus.Timepoint: Duration in minutes. Mean Arterial Pressure, Heart Rate, Central Venous Pressure, Carotid Artery Blood Flow, Carotid Artery Flow Time and Respiratory Variation in carotid artery peak systolic velocity will be recorded approximately 15 min after anaesthetic induction and 10 min after a fluid challenge.—

Secondary

MeasureTime frame
NOT APPLICABLETimepoint: NOT APPLICABLE—

Countries

India

Contacts

Public ContactDr Saba Khan

Jawaharlal Institute of Postgraduate Medical Education and Research

jipmermishra@gmail.com9344668104

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026