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Effect of laser on herpes viruses and on inflammatory mediators in patients with gum disease

â??Effect of diode laser as an adjunct to scaling and root planing on herpes viruses and on the mRNA expression of IFN-λ1 in the GCF of chronic periodontitisâ??- A Polymrase chain reaction study.

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018650
Enrollment
140
Registered
2019-04-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: not applicable: effect of diode laser and scaling and root planing on herpes viruses and interferon lamda 1 in patient with chronic periodontitis Intervention2: Diode laser therapy and

Sponsors

Rajarajeshwari Dental College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Systematically healthy patients and showing the absence of clinical manifestations of periodontal disease. 2)Chronic periodontitis patients having at least 20 natural teeth and minimum of 6 teeth with periodontal pockets >= 5mm and clinical attachment level >= 3-4mm. 3)All the patients should be systematically healthy and should not have received periodontal treatment for last 6 months prior to the clinical examination and sampling.

Exclusion criteria

Exclusion criteria: 1)Smokers 2)Systemic diseases like diabetes mellitus, heart diseases, rheumatoid arthritis, hepatitis and other systemic diseases that can alter the course of periodontal disease. 3)Diseases of oral hard and soft tissue except caries and periodontitis. 4)Subjects on any medication taken within last 6 months which may alter the periodontal status. 5.Pregnant and lactating mothers.

Design outcomes

Primary

MeasureTime frame
level of herpes viruses and interferon lambda 1 before and after treatmentTimepoint: baseline, immediately after treatment, at weeks

Secondary

MeasureTime frame
level of herpes viruses and interferon lambda 1 after scaling and root planing and diode laser therapyTimepoint: baseline, immediately after treatment, at 6 weeks

Countries

India

Contacts

Public ContactDrGeetha k

Rajarajeshwari dental college and hospital

drspbmath@gmail.com9901759011

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026