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Effect of different anesthetic injections on success rate of the injections while managing a painful tooth

Effect of varying concentrations of epinephrine in 2% lidocaine on the anesthetic success rate of intraligamentary injections in patients with symptomatic irreversible pulpitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018643
Enrollment
100
Registered
2019-04-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: supplementary intraligamentary injections of 2% lidocaine with 1:80 000 epinephrine: All patients will receive a primary inferior alveolar nerve block injection using 1.8 mL of 2% lidoc

Sponsors

Faculty of Dentistry self funded
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a. Symptomatic carious exposed mandibular first or second molars. b. Positive and prolonged response to thermal sensitivity tests and electric pulp test. c. Vital coronal pulp on access cavity preparation. d. American Society of Anesthesiologists class I or II medical history. e. Ability to understand the use of pain scales.

Exclusion criteria

Exclusion criteria: a. Active pain in more than 1 teeth. b. Teeth with fused roots. c. Radiographic evidence of an extra root. d. Large restorations with overhanging margins. e. Full crowns or deep periodontal pockets. f. Known allergy or contraindications to any content of the local anesthetic solution. g. History of known or suspected drug abuse. h. Taking any drugs which could affect the pain perception, e.g, opiods, antidepressants, anticonvulsants, muscle relaxants, anxiolytics, sedatives, nsaids. 23 i. Pregnant or breastfeeding patients.

Design outcomes

Primary

MeasureTime frame
The primary outcome (endpoint) will be defined as â??success or failureâ?? which will be indicated as the ability to undertake pulp access and canal instrumentation with no or mild pain.Timepoint: The primary outcome (endpoint) will be defined as â??success or failureâ?? which will be indicated as the ability to undertake pulp access and canal instrumentation with no or mild pain.

Secondary

MeasureTime frame
The secondary outcome will be the evaluation of heart rate.Timepoint: Immediately after supplementary intraligamentary injections.

Countries

India

Contacts

Public ContactVivek Aggarwal

Jamia Millia Islamia

drvivekaggarwal@gmail.com9818188358

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026