Health Condition 1: E559- Vitamin D deficiency, unspecified
Conditions
Interventions
Intervention1: vitamin D: single oral dose of 150,000 IU Vitamin D in obese and non-obese children in age group 5-12 years who are vitamin D deficient
Control Intervention1: NIL: NIL
Sponsors
Dr Medha Mittal
Eligibility
Inclusion criteria
Inclusion criteria: Cases- Obese Indian children (Obesity as defined by BMI more than 27 th adult equivalent of Indian Academy of Pediatrics BMI charts) of age group 5 to 12 years presenting to Out-patient clinic and pediatric endocrinology clinic at Chacha Nehru Bal Chikitsalaya, Delhi will be screened and included in the study if their vitamin D levels are less than 20 ng/ml. Controls- Apparently healthy children, not overweight or obese, of age group 5- 12 years presenting to pediatric OPD for minor complaints (like cough, coryza for less than 5 days) will be screened for vitamin D deficiency and included in the study if their vitamin D levels are less than 20 ng/ml.
Exclusion criteria
Exclusion criteria: 1. Children with confirmed or suspected malabsorption, renal or hepatic disorders. 2. Children who have received vitamin D in therapeutic doses in last 6 months. 3. Children on psoralen and ultraviolet A therapy (PUVA) for some skin disorder. 4. Children who have received drugs that may interfere with vitamin D metabolism like anticonvulsants, steroids, chemotherapy, antitubercular drugs, H2 Blockers, and thiazide diuretics and those on any herbal or ayurvedic medications. 5. Children with any known systemic illness or endocrine or metabolic disorder known to be associated with obesity either before or during the course of study or subjects with symptoms suggestive of hypothalamic obesity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of rise in serum vitamin D levels from baseline at 1-month post supplementation with single 150,000 IU oral dose of vitamin D in obese vs nonobese vitamin D deficient children in age group 5-12 years.Timepoint: Before giving Vitamin D and 1 month post Vitamin D supplementation | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypercalcemia, HypercalciureaTimepoint: 1 week and 1 month after Vitamin D dose | — |
Countries
India
Contacts
Public ContactDr Akshay Tayde
Chacha Nehru Bal Chikitsalaya, Delhi
Outcome results
None listed