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COMPARE THE ANTI-INFLAMMATORY EFFECT OF TWO DRUGS WHICH USED TO RELIEVE THE PAIN IN DENTAL EXTRACTIONS

COMPARISON BETWEEN THE ANTI-INFLAMMATORY EFFECT OF TRAMADOL AND KETOROLAC BY DETERMINING THE LEVELS OF SERUM C- REACTIVE PROTEIN AFTER REMOVAL OF IMPACTED THIRD MOLAR

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018620
Enrollment
40
Registered
2019-04-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Tab.tramadol: Group 1 participants will receive tab.tramadol 50 mg every 8 hours after food post operatively for 3 days Intervention2: Tab.ketorolac: Group 2 participants will receive t

Sponsors

Dr Yazhini R
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age 18 or above who have impacted third molar which is indicated for removal under local anaesthesia

Exclusion criteria

Exclusion criteria: 1. patients who are on antibiotics and analgesics pre-operatively. 2. patients who are on steroidal therapy. 3. patients who are allergic to the antibiotics and pain killers. 4. patients with pre existing systemic inflammatory disorders. 5. patients with previous or existing cardiovascular diseases, smokers, diabetes mellitus. 6. patients having periodontitis. 7. patients who has h/o peptic ulcer/ gastric ulcer / GI bleeding/ renal disorders.

Design outcomes

Primary

MeasureTime frame
Identification of anti inflammatory efficiency of drugs which is commonly used as analgesics in dental therapyTimepoint: 72 hours

Secondary

MeasureTime frame
Opiod analgesics also have anti inflammatory propertyTimepoint: 6 months

Countries

India

Contacts

Public ContactDr Yazhini R

Sree Mookambika Institute of Dental Sciences

sajeshnair79@yahoo.co.in9486941236

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026