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Minimising nasal bleeding by application of decongestant drops before putting tube through nostrils

Comparative efficacy of routinely used two different concentrations of intranasal topical adrenaline and xylometazoline to reduce fiberoptic-guided nasotracheal intubation associated epistaxis - CETFONE

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/04/018616
Enrollment
180
Registered
2019-04-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

None listed

Sponsors

Sanjay Gandhi Postgraduate Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Male and female patients of age 18- 65 years with American Society of Anaesthesiologists- Physical Status Grade 1 and 2 posted with indication for nasotracheal intubation i.e. undergoing surgery involving oral cavity, mandible, maxilla, thyroid, neck, difficult airway with decreased mouth opening, cervical spine, etc

Exclusion criteria

Exclusion criteria: 1) Patients who shall not give consent 2) Patients with nasal pathology (septal deviation, turbinate hypertrophy, nasal polyp and trauma) 3) Patients with history of common cold during prior 2 weeks or treatment with nasal decongestants, anti-histamines, NSAIDS 4) Patients with coagulopathy and on anticoagulants 5) Patients with drug allergy, chronic pain syndrome, on analgesic medication 6) Pregnant patients

Design outcomes

Primary

MeasureTime frame
Comparison of incidence and severity of epistaxis during fiberoptic-guided nasotracheal intubationTimepoint: At the time of intubation

Secondary

MeasureTime frame
1) Hemodynamic changes following administration of topical vasoconstrictor agents 2) Patient discomfort, pain and satisfaction scoring 24 hours after extubation Timepoint: 1)Hemodynamic changes at time 0 minute, 1 minute, 10 minutes following administration of topical vasoconstrictor agents 2) Patient discomfort, pain and satisfaction scoring 24 hours after extubation

Countries

India

Contacts

Public ContactShruti Somani

Sanjay Gandhi Postgraduate Institute of Medical Sciences

shrutisomani12@gmail.com9450344971

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026