Health Condition 1: G808- Other cerebral palsy
Conditions
Interventions
Intervention1: Gabapentin and trihexyphenidyl: Gabapentin 15-20 mg/kg/day in single dosage and trihexyphenidyl 0.2-2 mg/kg/day in three divided dosages (with upward dose escalation as 0.2 mg/kg/day in
Sponsors
JAYA SHANKAR KAUSHIK
Eligibility
Inclusion criteria
Inclusion criteria: Children aged between 3-9 years with dyskinetic cerebral palsy (Gross Motor Functional Classification System 4-5).
Exclusion criteria
Exclusion criteria: I. Children who have undergone any surgical such as orthopedic surgery or botulinum toxin injection in the preceding six months. II. A neurological or neurodegenerative condition known to mimic cerebral palsy including those with diurnal variations, parkinsonian features, suspected inborn errors of metabolism, or those with presumed genetic causes. III. Children with known renal, pulmonary, cardiac or hepatic dysfunction. IV. Children with associated drug-resistant epilepsy. V. Children with known hypersensitivity to the study drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Dyskinesia impairment scale scoreTimepoint: Baseline, 4 weeks and 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 3. International Classification of Functioning, Disability and Health-Children and Youth Version gradesTimepoint: baseline, 4 weeks and 12 weeks;Total dystonia severity assessment plan scoreTimepoint: baseline, 4 weeks and 12 weeks | — |
Countries
India
Contacts
Public ContactSonu Kumar
Pt .B .D .Sharma, PGIMS
Outcome results
None listed