Effect of tablet "Riluzole" in improving neurological outcomes in Cervical Spine injured patients.

Role of Riluzole in acute traumatic Cervical Spinal Cord injury with incomplete neurological deficit. A Prospective,Randomised control study.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/04/018596

Enrollment

Registered

2019-04-15

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S140- Concussion and edema of cervical spinal cord

Interventions

Intervention1: Tablet Riluzole: Tablet Riluzole will be given to a case group of acute traumatic Cervical Spinal Cord Injury patients. Tablet Riluzole will be given orally in dose of 100mg BD (loading

Eligibility

Inclusion criteria

Inclusion criteria: 1.SCI presenting within 72 hours of injury 2.Level C3-C8 3.Incomplete injury (ISNCSCI grade B, C, D)

Exclusion criteria

Exclusion criteria: 1.Penetrating injury 2.Significant head(GCS 3.Pre-existing renal/ liver disease 4.Concomitant use of other drugs 5.Pregnancy

Design outcomes

Primary

Measure	Time frame
Change in ISNCSCI grade, Motor and Sensory scores at 6monthsTimepoint: Change in ISNCSCI grade, Motor and Sensory scores at 6 months	—

Secondary

Measure	Time frame
Spinal cord independence measure (SCIM 3) SF-36 (Health related quality of life) NRS for pain Timepoint: 6months	—

Countries

India

Contacts

Public ContactK Dinesh

Ganga Hospital, Coimbatore, Tamil Nadu

kumarasamydinesh@gmail.com9843478578

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026