Health Condition 1: 4- Measurement and Monitoring
Conditions
Interventions
Intervention1: Muscle Relaxant drug: Administration of Muscle Relaxant Cisatracurium and atracurium per orally for intubation in abdominal surgeries.
Dose of cistracurium 0.1mg/kg
Dose of atracurium
Sponsors
Indira Gandhi Institute of Medical Sciences
Rahul Ranjan
Eligibility
Inclusion criteria
Inclusion criteria: Needing general anaesthesia and intubation ASA grade 1 & 2 Weight 50 to 70 kgs
Exclusion criteria
Exclusion criteria: Patient refusal Patient needing emergency surgery Patients with coexisting morbidities. Any history of allergic reaction to any drug involved Anticipated difficult airway
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Study effect of cisatracurium and atracurium on intubation and hemodynamic effectsTimepoint: From administration of drug to completion of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the effect on difficulty of laryngoscopy, vocals cords movement and position, cough, jaw relaxation, limb movement. Timepoint: From administration of muscle relaxant until the maximal suppression.;To compare for signs of histamine release clinically through skin changesTimepoint: From administration of drug till the surgery completes;To compare the intraoperative hemodynamic changes including heart rate, mean arterial blood pressure, oxygen saturation and end tidal carbon dioxide.Timepoint: From administration of drug and every 5 minutes until the surgery completes | — |
Countries
India
Contacts
Public ContactDr Prof Ajit Gupta
Indira Gandhi Institute of Medical Sciences
Outcome results
None listed