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A COMPARATIVE STUDY BETWEEN TWO DIFFERENT DOSES OF ORAL PREGABALIN TO ATTENUATE HAEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION

A COMPARATIVE STUDY BETWEEN TWO DIFFERENT DOSES OF ORAL PREGABALIN TO ATTENUATE HAEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018556
Enrollment
100
Registered
2019-04-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: Oral pregabalin 150 mg: A COMPARATIVE STUDY BETWEEN ORAL PREGABALIN 150 AND 75 MG TO ATTENUATE HAEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION Control Intervention1:

Sponsors

JLN MEDICAL COLLEGEAJMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients of ASA grade 1 and 2 aged between 18 and 55 years of either sex posted for elective surgeries under general anaesthesia.

Exclusion criteria

Exclusion criteria: 1. ASA grade III and above. 2. Age 55 years. 3. Patients with severe systemic disease like IDDM, uncontrolled hypertension, kidney and liver disease, severe respiratory disease. 4. Seizure disorder. 5. Coronary artery disease or recent history of MI. 6. Anticipated difficult intubation. 7. Body weight >100 kg or obese. 8. Pregnant and lactating women. 9. Mentally impaired patients. 10. Patients of psychiatric disorders and sleep disorders. 11. Patients on steroids since last 6 months. 12. Hypersensitivity to study drugs.

Design outcomes

Primary

MeasureTime frame
â?? Haemodynamic changes or response (SBP, DBP, MAP and HR)Timepoint: 6 MONTHS—

Secondary

MeasureTime frame
â?? Any significant side effects or complicationsTimepoint: 6 MONTHS;â?? Level of Sedation.Timepoint: 6 MONTHS—

Countries

India

Contacts

Public ContactDR VEENA PATODI

JLN medical college Ajmer

veenapatodi@gmail.com9414008276

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026