Efficacy of pre emptive epidural dexmedetomidine in patients with upper abdominal surgeries under general anaesthesia.

To assess the efficacy and safety profile of pre-emptive epidural dexmedetomidine in the patients undergoing upper abdominal surgery under general anaesthesia:A prospective randomised double blind study - Not applicable

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/04/018529

Enrollment

Registered

2019-04-10

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K565- Intestinal adhesions [bands] withobstruction (postinfection) Health Condition 2: K77- Liver disorders in diseases classified elsewhere Health Condition 3: K831- Obstruction of bile duct Health Condition 4: K315- Obstruction of duodenum Health Condition 5: K458- Other specified abdominal hernia without obstruction or gangrene Health Condition 6: K868- Other specified diseases of pancreas

Interventions

Intervention1: Epidural: Epidural anasethesia for upper abdominal surgery Control Intervention1: Injection Dexmedetomidine: To assess the efiicacy and safety profile of pre-emptive epidural dexmedetom

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and 2 planned for upper abdominal surgery

Exclusion criteria

Exclusion criteria: known allergy to study drug suspected coagulopathy infection at site of epidual cardiac or renal disease neurological illness deformity of spine

Design outcomes

Primary

Measure	Time frame
Analgesic efficacy of epidural Dexmedetomidine will be assessed bu VAS score. Its safety will be assessed by monitoring vitals(BP, Heart rate, SpO2) and sedation(Ramsay sedation score)Timepoint: Vitals will be monitored intraoperatively as well as postoperatively for 24 hrs.Sedation will be asseseed for 24 hours postoperatively	—

Secondary

Measure	Time frame
To evaluate the effect of dexmdetomidine on perioperative hemodynamics requirment of anaesthetic agent and post-operative analgesiaTimepoint: post-operative till 24hours	—

Countries

India

Contacts

Public ContactDr Indira kumari

MB hospital udaipur rajasthan

dr_ikumari@hotmail.com9414176760

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026