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Sepsis is a condition of newborn due to infection in the body system. Here we are diagnosing sepsis by using a protein from the saliva of the baby.

Diagnostic utility of quantitative salivary CRP as a marker of sepsis in neonates

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/04/018490
Enrollment
60
Registered
2019-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P36- Bacterial sepsis of newborn

Interventions

None listed

Sponsors

None
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All newborns with gestational age >=32 weeks and birth weight >=1000g will be screened for possible sepsis if they present beyond 24 hr. of age with one or more of the following clinical signs - 1. history of feeding difficulty, 2. movement only when stimulated, 3. temperature =37.5oC, 4. respiratory rate over 60 breaths per minute, 5. severe chest in drawing and 6. history of convulsions

Exclusion criteria

Exclusion criteria: 1. Meconium aspiration syndrome 2. Hypoxic ischemic encephalopathy 3. Neonates requiring surgery 4. CNS malformation 5. Metabolic disorders 6. Chromosomal abnormalities

Design outcomes

Primary

MeasureTime frame
Correlation between salivary and serum CRP Timepoint: After completing recruitment—

Secondary

MeasureTime frame
Optimum cut off of salivary CRP for diagnosis of sepsis (blood culture positive)Timepoint: After completing recruitment—

Countries

India

Contacts

Public ContactDr Nitin M

Maulana Azad Medical College

nitinmachar@gmail.com9743288168

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026