Health Condition 1: M519- Unspecified thoracic, thoracolumbar and lumbosacral intervertebral disc disorder
Conditions
Interventions
Control Intervention1: Propofol, Sevoflurane and Desflurane: Comparing recovery profiles of patients undergoing surgery under propofol, sevoflurane or desflurane anaesthesia
Sponsors
SGPGI
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA grade I and II 2. Age between 18 to 65 year 3. Patients of either gender 4. Education level minimum up to 8th standard 5. Single or two level disease necessitating decompression/discectomy without instrumentation
Exclusion criteria
Exclusion criteria: 1. Patient refusal 2. Inability to read or speak or communicate 3. Patients with psychiatric disorders/behavioral impairment or on antipsychotic drugs 4. Patients with significant hepatic, cardiovascular,pulmonary or renal disorders 5. Morbid obesity 6. Patients with allergy to study drugs or history of malignant hyperthermia 7. Chronic drug/alcohol abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) To compare the preoperative versus postoperative cognitive and psychomotor recovery profiles of patients undergoing lumbar laminectomy and discectomy under general anaesthesia maintained with propofol, sevoflurane or desflurane.Timepoint: Thrice preoperatively. Post extubation at 15 minutes, 30 minutes, 1 hour, 2 hours, 3 hours and at 4 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) To compare the incidences of postoperative complications like headache, giddiness, nausea, vomiting or pain at injection sites. 2) To compare the time taken by subjects administered these three anaesthetic regimens to achieve a modified Aldreteâ??s Score of 9. 3) To compare the satisfaction of the patients regarding the quality of anaesthesia Timepoint: After 4 hours post intubation | — |
Countries
India
Contacts
Public ContactDr Amit Kumar Verma
SGPGI, Lucknow
Outcome results
None listed