Oral Griseofulvin and topical 1%Clotrimazole cream , are they still effective and safe?

A study of Efficacy and Safety of Oral Griseofulvin and topical 1%Clotrimazole cream in griseofulvin naive cases of Tinea cruris and/or corporis-An Interventional Study - ESGC

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/04/018461

Enrollment

160

Registered

2019-04-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue

Interventions

Intervention1: not applicable: not applicable Intervention2: oral griseofulvin 10mg/kg ,topical 1% clotrimazole cream: griseofulvin 10mg/kg three or two times depending upon the weight , topical 1% cl

Eligibility

Inclusion criteria

Inclusion criteria: griseofulvin naive

Exclusion criteria

Exclusion criteria: pregnancy, lactation, systemic illness

Design outcomes

Primary

Measure	Time frame
Complete clearance that is no active lesion with negative KOH test. Partial clearance which is reduction in symptoms with or without positive KOH. Non clearance is no reduction in symptoms and negative KOH even after appropriate duration of therapyTimepoint: week 0,2,4,6,8	—

Secondary

Measure	Time frame
Adverse events ranging from mild headache, urticaria and nausea to hepatotoxicity and Steven Johnson syndromeTimepoint: week 2,4,6,8	—

Countries

India

Contacts

Public ContactAshutosh Pal

medical college baroda

ym11256@gmail.com9825917442

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026