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A clinical trial to compare the levels of INTERLEUKIN-1BETA ,an inflammatory biomarker around gingiva of orthodontic mini-implant during direct force delivery to mini-implant

Interleukin 1-Beta levels around orthodontic Mini-Implants during Direct loading

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018439
Enrollment
40
Registered
2019-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M264- Malocclusion, unspecified

Interventions

Intervention1: With orthodontic miniimplant assessing the levels of IL-IBeta levels from periminiimplant crevicular fluid.: comparing the levels on IL-1Beta levels in direct immediate and direct delay

Sponsors

Dr V Sarath kumar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a.age group-15-25 years irrespective of gender b.subject requiring bilateral first premolar extraction c.patient should be in healthy systemic condition d.no use of anti-inflammatory drugs in the 6 months preceding the beginning of study e.healthy periodontal tissue with generalized probing depth less than 3mm f.willing informed consent/assent

Exclusion criteria

Exclusion criteria: Not willing to give informed consent. Ho anti-inflammatory drug administration in 6 months preceding the study. Non compliant patient with inability to maintain oral hygiene. Patient with systemic conditions affecting bone metabolism and implant placement. Patient with history of prior orthodontic treatment.

Design outcomes

Secondary

MeasureTime frame
comparision of the levels of IL-1Beta levelsTimepoint: 4months

Primary

MeasureTime frame
levels of IL-1 BETA levels around orthodontic mini-implantsTimepoint: levels of IL-1 BETA levels around orthodontic mini-implants will be assessed during October -November 2020

Countries

India

Contacts

Public ContactDr V Sarath kumar

CDER,AIIMS,Division of Orthodontics

rituduggal@rediffmail.com7838390003

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026