Health Condition 1: M264- Malocclusion, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: a.age group-15-25 years irrespective of gender b.subject requiring bilateral first premolar extraction c.patient should be in healthy systemic condition d.no use of anti-inflammatory drugs in the 6 months preceding the beginning of study e.healthy periodontal tissue with generalized probing depth less than 3mm f.willing informed consent/assent
Exclusion criteria
Exclusion criteria: Not willing to give informed consent. Ho anti-inflammatory drug administration in 6 months preceding the study. Non compliant patient with inability to maintain oral hygiene. Patient with systemic conditions affecting bone metabolism and implant placement. Patient with history of prior orthodontic treatment.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| comparision of the levels of IL-1Beta levelsTimepoint: 4months | — |
Primary
| Measure | Time frame |
|---|---|
| levels of IL-1 BETA levels around orthodontic mini-implantsTimepoint: levels of IL-1 BETA levels around orthodontic mini-implants will be assessed during October -November 2020 | — |
Countries
India
Contacts
CDER,AIIMS,Division of Orthodontics