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Efficacy of Ketorolac IV Versus wound instillation for post operative analgesia following thyroidectomy

Efficacy Of Ketorolac IV Versus Wound Instillation For Post Operative Analgesia following Thyroidectomy: A Prospective Randomised Comparative Double Blind Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018438
Enrollment
52
Registered
2019-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E079- Disorder of thyroid, unspecified

Interventions

Intervention1: ketorolac intravenous and ketorolac instillation: in both groups intravenous and instillation,only 30 mg ketorolac,single dose only we will give before closure of the incission Control

Sponsors

NIZAMS INSTITUTE OF MEDICAL SCIENCES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 18 to 60 years of ASA physical status I and II with informed written consent posted for elective thyroid surgeries will be included in the study.

Exclusion criteria

Exclusion criteria: Patient refusal -GI bleeding disorder - Allergy or sensitive to ketorolac, aspirin, or other NSAID - Severe Cardiac,Renal, Hepatic insufficiency - Coagulopathy, Severe bronchial asthma. -Radiotherapy -Previous analgesic and anti inflammatory treatment. -Neurological alteration. - Pregnancy n lactation

Design outcomes

Primary

MeasureTime frame
-Primary outcome of this study will be the efficacy of I V ketorolac vs wound instillation with ketorolac on reducing post operative pain using VAS score in post operative patients for thyroid surgery and requirement of rescue analgesics along with haemodynamic changes and anxiety.0,4,12,24hrsTimepoint: 24hrs

Secondary

MeasureTime frame
Incidence of side effects including nausea, vomiting shivering post op bleeding. Incidence of nausea and vomiting estimated at 0,4 ,12 and 24hrs For severe nausea and episodes of vomiting , I V administration of ondansetron 4mg will be given as a rescue anti emetic. Timepoint: 24hrs

Countries

India

Contacts

Public ContactNIRMALA J

NIZAMS INSTITUTE OF MEDICAL SCIENCES

njonnavithula@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026