Effect of Carica Papaya Leaf extract capsule on platelet counts in Dengue fever

Profile of Dengue Fever and effect of carica papaya leaf extract capsule on platelet counts and clinical bleeding - CARDEN

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/04/018435

Enrollment

176

Registered

2019-04-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A90- Dengue fever [classical dengue]

Interventions

Intervention1: Carica papaya leaf extract capsule: Carica papaya leaf extract capsule given 1100 mg thrice daily orally for 5 days Control Intervention1: PLACEBO: Multivitamin capsule

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients aged more than 18 yrsadmitted with fever and dengue Ns1Ag (OR) IgM positive

Exclusion criteria

Exclusion criteria: 1. Patients with chronic liver disease 2. Patients with dengue co-infectionlike malaria , typhoid , scrub typhus. 3. Patient with platelet disorders (eg:Immune thrombocytopenic purpura) 4. Pregnant women with dengue fever.

Design outcomes

Primary

Measure	Time frame
1. To describe the clinical profile of dengue fever in adult patients admitted in PIMS 2. To determine the effect of carica papaya leaf extract capsuleon platelet counts in adult patients of dengue fever admitted in PIMS Timepoint: 8 months	—

Secondary

Measure	Time frame
Whether carica papaya leaf extract capsule reduce hemorrhagic manifestationsTimepoint: 10 months	—

Countries

India

Contacts

Public ContactDinesh babu

pondicherry institute of medical sciences

drsudhagar7893@gmail.com09944667893

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026