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To see if there is any difference in post operative agitation in children having adenotonsilectomy/tonsilectomy surgery under general anesthesia with sevoflurane with two different doses of the same drug,dexmedetomidine

THE EFFECT OF INTRAOPERATIVE DEXMEDETOMIDINE IN TWO DIFFERENT DOSAGES ON EMERGENCE AGITATION IN CHILDREN UNDERGOING ADENOTONSILECTOMY/TONSILECTOMY UNDER SEVOFLURANE ANAESTHESIA-A PROSPECTIVE DOUBLE BLIND RANDOMIZED CONTROL TRIAL - EODOEA

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018431
Enrollment
82
Registered
2019-04-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients with adenotonsilectomy

Interventions

Intervention1: DEXMEDETOMIDINE : 0.3mcg/kg/hour : GROUP A : 0.3mcg/kg/hour DURATION : 1-1.5 hours Control Intervention1: DEXMEDETOMIDINE: 0.5mcg/kg/hour: GROUP B : 0.5mcg/kg/hour DURATION:1-1.5hours

Sponsors

Pondicherry institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age group of 5 â?? 14 years 2.Sex : both genders 3.American society of anaesthesiologists(ASA) physical status I/II. 4.Patients undergoing Adenotonsilectomy surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: 1.Children with known allergy to study medication. 2.Children with devepolmental delay and mental retardation. 3.Liver, renal, cardiac, and respiratory disorders. 4.Children receiving medications known to interact with Dexmeditomidine such as furosemide, lorazepam and diphenhydramine

Design outcomes

Primary

MeasureTime frame
To determine the effect of two different dosages of intraoperative dexmedetomidine on the incidence of emergence agitation in children aged 5 â?? 14 yrs undergoing Adenotonsilectomy/tonsilectomy anaesthetized with Sevoflurane in PIMSTimepoint: 1-1.5hours—

Secondary

MeasureTime frame
1.Hemodynamic parameters like heart rate, blood pressure, saturation, respiratory rate. 2.onset and the duration of pain Timepoint: 1-1.5hours—

Countries

India

Contacts

Public ContactDrMAMIE ZACHARIAH

PONDICHERRY UNIVERSITY

mamiezac@gmail.com04132651127

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026