Comparing the effect of two different doses of injection ketamine(induction drug) with tramadol(opioid) on reducing postoperative analgesic requirement in patients undergoing laparoscopic surgeries under general anaesthesia.

Comparison of two different doses of ketamine with tramadol as preemptive analgesia in laparoscopic surgeries

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2019/04/018422

Enrollment

Registered

2019-04-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K811- Chronic cholecystitis

Interventions

Intervention1: Inj.Tramadol 1mg/kg,Inj.Ketamine 0.25mg/kg,Inj.Ketamine 0.5mg/kg: Inj.Tramadol 1mg/kg/iv over 10minutes,Inj.Ketamine 0.25mg/kg/iv over 10minutes,Inj.Ketamine 0.5mg/kg/iv over 10minutes.

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II patients Surgeries like laparoscopic cholecystectomy and appendicectomy.

Exclusion criteria

Exclusion criteria: Patients who are allergic to study drug. patients on antipsychiatric medications,sedatives,opioids and antidepressants. BMI >30kg/m2

Design outcomes

Primary

Measure	Time frame
Haemodynamic response to intraperitoneal gas insufflation. Timepoint: Till 15 minutes intraoperative post insufflation period.	—

Secondary

Measure	Time frame
1.Total number of patients requiring supplemental analgesia. 2.Time of requirement of first rescue analgesia in each group. 3)Total opioid requirement in 24hours postoperative period.Timepoint: Till 24 hours in the postoperative period.	—

Countries

India

Contacts

Public ContactA Arun Kumar

Chettinad Hospital and Research Institute,Kelambakkam

pugalenthi08@yahoo.co.in9489404818

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026