Health Condition 1: J454- Moderate persistent asthma
Conditions
Interventions
Intervention1: shirashadi agad 40 ml,BD,empty stomach for 1 month
amalaki rasayan 5gm,BD,for 2 month: â?¢ Shirishadi Agad in the dose of 40 ml in the forms of decoction twice a day for 1 month.
â?¢ Du
Sponsors
All India Institute of Ayurveda
Eligibility
Inclusion criteria
Inclusion criteria: Patients of allergic asthma presenting with Tamaka Shwasa lakshna Total serum IgE concentration greater than or equal to 30 and less than or equal to 700 Intenational units per millilitre at Visit 0 History of at least moderate persistent allergic asthma (consistent with Global Initiative for Asthma [GINA] guidelines of more than 1 year in duration on a stable asthma treatment regimen including inhaled corticosteroids for the preceding 4 weeks An FEV1 while withholding short acting beta agonists for at least 6 hours and long acting beta agonists for at least 12 hours, of greater than or equal to 75 percentage of the predicted value at Visit 0 Evidence of reversible airway obstruction, as defined by an increase in FEV1 of more than or equal to 12 percentage between 20 to 30 minutes after 4 puffs (or less at the discretion of the investigator) of inhaled short-acting beta-agonist administration at Visit 0 or within the preceding year Pre-specified level of nocturnal asthma symptoms Non-smoker for at least 1 year prior to Visit 0, with a smoking history of no more than 10 pack-years (that is 1 pack,20 cigarettes per day for 10 years)
Exclusion criteria
Exclusion criteria: History of intubation for asthma Asthma exacerbation requiring treatment with systemic steroids within the preceding 3 months Asthma exacerbation requiring treatment in an emergency department or a hospital admission in the preceding 6 months Upper respiratory tract infection or sinusitis within the preceding 4 weeks History of an anaphylactic allergic reaction History of treatment with immunotherapy to any allergen within past 3 years History of aspirin or non steroidal anti inflammatory drug (NSAID) related asthma patients could have been included in NSAIDs use was avoided for the duration of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Doshik Anshansa kalpna (changes in total Asthma symptom score)Timepoint: Thirty days | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction in IgE level. Non-allergic response on exposure of allergen. Absolute eosinophil count Overall Improvement in Quality of life. Improvement in Agni Bala, Deha Bala and Chetas Bala as per Ayurveda Timepoint: Thirty days | — |
Countries
India
Contacts
Public ContactDr Prasanth Dharmarajan
All India Institute of Ayurveda
Outcome results
None listed