FindTrial
Sign In

A study to compare the effect of two medicines on blood pressure while the patients undergo a procedure of surgery by laparascopy under full anaesthesia.

A comparative study of infusion dexmedetomidine and infusion magnesium sulphate on attenuation of hemodynamic changes in laparoscopic surgery under general anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/04/018356
Enrollment
150
Registered
2019-04-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Control Intervention1: Dexmeditomidine vs Magnesium Sulfate: Dexmeditomidine loading dose 1mcg/kg in 20ml normal saline over 15 minutes intravenously. Infusion rate 0.4 mcg/kg/hr intravenously. Magne

Sponsors

Indira Gandhi Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA physical status 1 and 2 Patients undergoing laparoscopic surgery Patient willing to participate

Exclusion criteria

Exclusion criteria: Patients refusal to participate Patients with pregnancy Morbid Obesity Full stomach and emergency surgery Patients with suspected difficult laparoscopic surgery Patients sensitive to drug

Design outcomes

Primary

MeasureTime frame
Study of drug dexmedetomidine and infusion of magnesium sulphate on hemodynamic responses.Timepoint: From administration of drug to upto 6 hours in post anaesthesia care unit.—

Secondary

MeasureTime frame
To study the relative efficacy of infusion of dexmedetomidine and infusion of magnesium sulphate on hemodynamic responses in laparoscopic surgery under general anaesthesia.Timepoint: From administration of drug to upto 6 hours in post anaesthesia care unit.—

Countries

India

Contacts

Public ContactDr Prof K H Raghwendra

Indira Gandhi Institute of Medical Sciences

dr.khraghwendra@ymail.com9835092798

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026