Health Condition 1: R638- Other symptoms and signs concerning food and fluid intake
Conditions
Interventions
Intervention1: Half Normal Saline(0.45%): Half Normal Saline (0.45% saline) as calculated by Holliday Segar Formula
Control Intervention1: Normal Saline(0.9%).: Normal Saline (0.9% saline) as calculat
Sponsors
Director LHMC
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children in the age group of 1-18 years admitted in Kalawati Saran Children Hospital ,New Delhi. 2. Receiving intravenous fluid within 24 hrs of admission.
Exclusion criteria
Exclusion criteria: 1. Patients who have already received some intravenous fluid at the time of admission. 2.Patients with any neurological complaints eg. seizures, altered sensorium, lethargy, meningitis etc.; acute kidney injury; chronic kidney disease ; severe acute malnutrition; dehydrated or in shock patients ; those having ongoing blood loss or gastrointestinal losses; those receiving ORS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome variable: Proportion of children developing hyponatremia (serum sodium 135meq/L) at 0 and 24hr of receiving intravenous maintenance fluids . Timepoint: at 0 hours and at 24 hours of administering fluid therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Mean serum sodium levels. 2. Percentage of patients who develop symptomatic hyponatremia ie. seizures (not attributable to other cause). 3. The urine and blood osmolality at 0 and 24 hours. 4. The blood urea and serum creatinine levels Timepoint: at 0 hours and at 24 hours of administering fluid therapy | — |
Countries
India
Contacts
Public ContactDr Harish K Pemde
LHMC New Delhi
Outcome results
None listed