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Measurement Of Body Water Status In Patients With Pheochromocytoma And Paraganglioma Using Ultrasound.

Preoperative Intravascular Volume Status Measured By Inferior Vena Cava Collapsibility Index In Patients With Pheochromocytoma And Paraganglioma Undergoing Surgical Tumour Removal- A Prospective Observational Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/03/018334
Enrollment
40
Registered
2019-03-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E278- Other specified disorders of adrenal gland

Interventions

Intervention1: Pheochromocytoma and Paraganglioma: Patients with proven functional pheochromocytoma or Paraganglioma who are on alpha adrenergic blockade therapy to control hypertension and are schedu

Sponsors

AII India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Group 1: 1. All functional pheochromocytoma and Paraganglioma patients scheduled for tumour removal. 2. Patients consenting for study. 3. Age group between 18 to 70 years. Group 2: 1. Controlled essential hypertension patients scheduled for any elective surgery. 2. Patients consenting for study. 3. Age group between 18 to 70 years.

Exclusion criteria

Exclusion criteria: Group1: 1. Normotensive pheochromocytoma patients. 2. Normotensive or hypertensive patients in whom functional status of adrenal tumour is ambiguous. 3. Patients with obesity. 4. Tricuspid regurgitation. 5. Cardiomyopathy with EF less than 40%. 6. Right sided heart disease. 7. Portal hypertension. 8. Obstructive lung disease. Group 2: 1. Patient with obesity. 2. Tricuspid regurgitation. 3. Cardiomyopathy with EF less than 40%. 4. Right sided heart disease. 5. Portal hypertension. 6. Obstructive lung disease. 7. Patients with restricted fluid intake due to any reason( CKD,SIADH).

Design outcomes

Primary

MeasureTime frame
Inferior vena cava collapsibility index greater than 40 percentTimepoint: Within 20 minutes prior to induction of anaesthesia—

Secondary

MeasureTime frame
Difference in IVC-CI between functional pheochromocytoma/ Paraganglioma patients and well controlled essential hypertension patientsTimepoint: Within 20 minutes prior to induction of anaesthesia;Intravenous fluid requirement in both groupsTimepoint: From induction of anaesthesia till skin closure;Vasopressor requirement in study groupTimepoint: From induction of anaesthesia till patient discharge from hospital—

Countries

India

Contacts

Public ContactPoornima Alias Diana R

AIIMS

rashmiramachandran1@gmail.com9811422188

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026