Does RAM Cannula, a nasal Interface, reduce nasal injuries in preterm infants supported on bubble CPAP?

RAM Cannula versus Hudson prongs for delivery of CPAP in preterm infants between 28 weeks to 34 weeks of gestation with birth weight more than or equal to 1000 grams with respiratory distress for reducing nasal injuries: A randomized control trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/03/018333

Enrollment

218

Registered

2019-03-29

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P229- Respiratory distress of newborn, unspecified

Interventions

Intervention1: CPAP RAMâ??s cannula group: The appropriate sized RAMâ??s cannula as per manufacturerâ??s instructions will be used for providing CPAP. Rams cannula would be fixed on the nose using a c

Eligibility

Inclusion criteria

Inclusion criteria: Neonates with gestational age between 28 weeks to 34 weeks and weighing more than or equal to 1000 grams and admitted to the NICU will be eligible for the study. Those with respiratory distress and in need of nasal CPAP will be enrolled in the study

Exclusion criteria

Exclusion criteria: Major Malformation Intubated in the labor room for respiratory distress

Design outcomes

Primary

Measure	Time frame
Incidence and severity of nasal injury at removal of CPAPTimepoint: 6 hours after removal of CPAP	—

Secondary

Measure	Time frame
Nasal Injury Score at Discharge, Need for Mechanical Ventilation. Duration of CPAP,change of interface, BPD, IVH, PVL, VAP, MortalityTimepoint: 6 hours after removal of CPAP and at Discharge from the Hospital	—

Countries

India

Contacts

Public ContactSHRAVANI REDDY

Fernandez Hospital

srinivasmurki2001@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 13, 2026