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The dose of injection noradrenaline for prevention of low blood pressure after spinal anaesthesia in elective Caesarean section

Optimal dose of prophylactic intravenous infusions of norepinephrine for prevention of hypotension post spinal anaesthesia in elective Caesarean section

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/03/018332
Enrollment
50
Registered
2019-03-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA2 parturients with singleton full term pregnancy for elective LSCS Health Condition 2: O746- Other complications of spinal andepidural anesthesia during labor and delivery

Interventions

Intervention1: Norepinephrine: First case receives 0.05 mcg/kg/min. The infusion rates will be adjusted and titrated depending on the systolic BP. If the Systolic BP is more than 20% of the baseline v

Sponsors

Dr LH Hiranandani Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All ASA2 parturients with singleton full term pregnancy for elective LSCS. Patients giving valid consent Gestational age 37 to 40 weeks

Exclusion criteria

Exclusion criteria: Patient refusal Patient on any medication that influences the cardiovascular system Patients with PIH/eclampsia Maternal heart disease or coagulopathies Placenta previa, uterine myomas Patients with contraindication to regional anaesthesia Inadequate action of spinal anaesthesia and conversion to general anaesthesia History of seizures or progressive neurologic disease

Design outcomes

Primary

MeasureTime frame
Prevention of HypotensionTimepoint: Intraoperative period post spinal anaesthesia

Secondary

MeasureTime frame
Incidence of nausea and vomiting, evaluation of fetal APGAR score at 0 and10 minsTimepoint: Intraoperative period and post operative period post spinal anaesthesia for nausea, vomiting and at 0 and 5 mins for APGAR score

Countries

India

Contacts

Public ContactVaralika Sharma

Dr. LH Hiranandani Hospital, Powai

meenoti@yahoo.com9920627839

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026