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Effect of cervical mucus removal on outcome of intrauterine insemination

Effect of cervical mucus removal prior to intrauterine insemination in unexplained infertility: randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/03/018326
Enrollment
60
Registered
2019-03-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R688- Other general symptoms and signs

Interventions

Intervention1: Cleaning of cervical mucus before intrauterine insemination: An insemination catheter will be used to remove cervical mucus from the cervical canal by passing the catheter repeatedly fr

Sponsors

No sponsor
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Duration of infertility at least one year 2. Primary or secondary infertility 3. Normal semen analysis based on World Health Organization criteia10 4. Age of female partner between 20-35 years 5. Female partnerâ??s body mass index: 18-27 6. No ovulatory dysfunction in female partner 7. Day two transvaginal scan within normal range (total antral follicle count of 10â??24) 8. Day two hormonal profile within normal range (follicular stimulating hormone 9. Normal thyroid function 10. Atleast one patent tube on hysterosalpingography or hysterolaparoscopy. 11. Normal uterine cavity on hysterosalpingography or hysteroscopy;

Exclusion criteria

Exclusion criteria: 1. More than three previous IUI attempts 2. Chronic medical illness 3. History of Breast or gynecological malignancy

Design outcomes

Primary

MeasureTime frame
The clinical pregnancy rate (defined as ultrasound evidence of pregnancy) per IUI cycle.1. Biochemical pregnancy rate, 2. Multiple pregnancy rates ( more than one gestational sac seen at 6 weeks). 3. Cycle cancellation rate due to risk of ovarian hyperstimulation syndrome Timepoint: 14 days after IUI

Secondary

MeasureTime frame
1. Biochemical pregnancy rate, 2. Multiple pregnancy rates (1 gestational sac seen at 6 weeks). 3. Cycle cancellation rate due to risk of ovarian hyperstimulation syndrome Timepoint: 14 days after IUI

Countries

India

Contacts

Public ContactRicha Vatsa

Postgraduate Institute of medical education and research, chandigarh

dr.richavatsa@gmail.com9810248161

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 11, 2026