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comparing the use of isobaric ropivacaine with buprenorphinelevobupivacaine with Buprenorphine during spinal anaesthesia reduces post surgical pain relief medication

Comparison of Isobaric Ropivacaine (0.75%) with Buprenorphine and Isobaric Levobupivacaine (0.5%) with Buprenorphine in patients undergoing surgeries under Subarachnoid block: A Prospective Randomized Double Blind Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/03/018299
Enrollment
70
Registered
2019-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Isobaric Ropivacaine (0.75%) with Buprenorphine and Isobaric Levobupivacaine (0.5%) with Buprenorphine: Isobaric Ropivacaine (0.75%) with Buprenorphine Isobaric Levobupivacaine (0.5%)

Sponsors

Aniruth Geethchand
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age group between 18 to 65 years. 2.American Society of Anesthesiologist (ASA) Grade I and II. 3.Lower abdominal surgeries 4.Lower limb orthopaedics surgeries 5.Both Elective and Emergency procedures 6.Duration of surgery >= 60 minutes

Exclusion criteria

Exclusion criteria: 1. Patients not willing for regional anesthesia. 2. Patients not willing to be in the study group. 3. Pregnant patients. 4. Known allergy to the study drugs. 5. Patients with Peripheral neuropathy

Design outcomes

Primary

MeasureTime frame
compare the efficacy of Isobaric Ropivacaine(0.75%) with Buprenorphine 0.2 ml(60µg) and Isobaric Levobupivacaine (0.5%)with Buprenorphine 0.2ml(60µg) in patients undergoing surgeries under Subarachnoid block. Timepoint: Onset of sensory block is defined as the time taken to achieve loss of temperature sensation at T8 dermatome using cold saline cotton swab. It will be assessed using Gromley and Hill 1996. Onset of motor block is defined as the time taken to achieve complete motor block which is graded according to modified Bromage scale Two segment regression of sensory block and motor regression time also be recorded.—

Secondary

MeasureTime frame
To compare onset and duration of sensory blockade. To compare onset and duration of motor blockade. To assess and compare the hemodynamics between both groups. To assess two segment sensory regression time. Side effects if any. Timepoint: Postoperative monitoring of pain will be assessed with visual analogue score (VAS) using a 10 cm line, where zero denotes no pain and 10 denotes worst possible pain. Pain score will be assessed post operatively every 30 minutes till the patient onset of pain. If patient requiring rescue analgesia Injection Tramadol 50 mg slow iv will be given and the study will be terminated. Patient will be monitored for recovery of motor function to a Bromage score of 1 for every 30 mins.—

Countries

India

Contacts

Public ContactAniruth Geethchand

Department of Anaesthesiology, Chettinad Hospital and Research Institute, Kelambakkam, Chennai

drbala.srmc@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026