Correlating the presence of the BRAF mutation to the outcome of post-surgical patients with odontogenic tumours

Significance of BRAF positivity in prognosis of odontogenic tumours

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/03/018297

Enrollment

Registered

2019-03-28

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C069- Malignant neoplasm of mouth, unspecified

Interventions

Intervention1: Testing BRAF positivity on pathology specimens: Using paraffin-wax specimens for testing BRAF positivity and correlating to clinical condition of the patient Control Intervention1: Not

Eligibility

Inclusion criteria

Inclusion criteria: Patients that have undergone treatment for odontogenic tumours at the Department of Oral and Maxillofacial surgery are included. Patients whose paraffin wax embedded tissue specimens are available at the Department of Oral Pathology and Microbiology are included.

Exclusion criteria

Exclusion criteria: Patients with other systemic disorders that increase likelihood of odontogenic tumours were excluded. Patients that are not on regular follow-up and those who were not provided treatment at KH, Manipal and those whose tissue specimens are not available, are excluded from the study.

Design outcomes

Primary

Measure	Time frame
Positivity Negative UndeterminedTimepoint: 3, 6, 9, 12 months	—

Secondary

Measure	Time frame
Not ApplicableTimepoint: Not Applicable	—

Countries

India

Contacts

Public ContactSai Nivedita JS

Manipal College of Dental Sciences, Manipal

adarsh.kudva@manipal.edu

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026